Lt. married Mary Cooke on 26 Dec 1645 in East Bridgewater, Plymouth, Massachusetts. Mary (daughter of Francis Cooke and Hester Le Mahieu) was born about 1626 in Plymouth, Plymouth, Massachusetts; died on 21 Mar 1715 in Middleboro, Plymouth, Massachusetts. [Group Sheet]

1. Adam Thompson was born before 26 Sep 1646 in Plymouth, Plymouth, Massachusetts; died about 1648 in Plymouth, Plymouth, Massachusetts.
2. John Thompson was born in Nov 1647 in Plymouth, Plymouth, Massachusetts; died on 11 Feb 1649 in Plymouth, Plymouth, Massachusetts.
3. John Thompson was born on 24 Nov 1649 in Plymouth, Plymouth, Massachusetts; died on 25 Nov 1725 in Middleboro, Plymouth, Massachusetts.
4. Mary Thompson was born on 16 Aug 1650 in Plymouth, Plymouth, Massachusetts; died after 15 Jun 1723 in Dartmouth, Bristol, Massachusetts.
5. Esther Tomson was born on 28 Jul 1652 in Barnstable, Plymouth, Massachusetts; died before 12 Sep 1706 in Weymouth, Norfolk, Massachusetts.
6. Elizabeth Thompson was born on 28 Jan 1654 in Barnstable, Plymouth, Massachusetts; died before 21 Sep 1717.
7. Sarah Thompson was born on 4 Apr 1657 in Barnstable, Plymouth, Massachusetts; died on 16 Jun 1696 in Plymouth, Massachusetts.
8. Lydia Thompson was born on 5 Oct 1659 in Barnstable, Plymouth, Massachusetts; died on 14 Mar 1742 in Middleboro, Plymouth, Massachusetts.
9. Jacob Thompson was born on 24 Apr 1662 in Barnstable, Plymouth, Massachusetts; died on 1 Sep 1726 in Middleboro, Plymouth, Massachusetts.
10. Thomas Thompson was born on 19 Oct 1664 in Barnstable, Plymouth, Massachusetts; died on 26 Oct 1742 in Halifax, Plymouth, Massachusetts.
11. Peter Thompson was born between 1666 and 1669 in Barnstable, Plymouth, Massachusetts; died before 29 Apr 1731 in Halifax, Plymouth, Massachusetts.
12. Mercy Thompson was born between 20 Apr 1671 and 19 Apr 1672 in Barnstable, Plymouth, Massachusetts; died on 19 Apr 1756 in Halifax, Plymouth, Massachusetts.